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Rotary movement of DNA rotors on nanopores. Prime row: raw movie from the Cy5 channel of each and every rotor. Middle row: corresponding one-particle localization final results of both finishes of the DNA rotors. The situation of the current body is marked as orange and blue dots, and also the trajectory of The ten frames before The present body is… Read More

‘Certainly, which is about ideal. I look for a Bodily idea of biological programs inside of a bottom-up way. I believe you could potentially distinguish three strains of research in my group at this time. The very first worries chromosome composition: how do you obtain a metre-very long DNA polymer folded and organised in this kind of microsc… Read More

Making use of single-molecule optical and AFM imaging and force-spectroscopy procedures, we request to unravel the mechanistic areas of the framework and dynamics of chromosomes. Our analysis interests consist of:Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular forms with recombination function.Dynamics of ini… Read More